Zhong D, Liu X, Khuri FR, Sun SY, Vertino PM, Zhou W.
LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins.
Cancer Res. 68(18):7270-7, 2008.
Kapoor-Vazirani P, Kagey JD, Powell DR, Vertino PM.
Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity.
Cancer Res. 68(16):6810-21, 2008.
Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM.
Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol Cell. 30(3):336-47, 2008.
Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI.
The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity.
Cancer Res. 68(3):740-8, 2008.
Evans CO, Moreno CS, Zhan X, McCabe MT, Vertino PM, Desiderio DM, Oyesiku NM.
Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses.
Pituitary. 2008 Jan 9; [Epub ahead of print]
Saxena NK, Vertino PM, Anania FA, Sharma D.
Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3.
J Biol Chem. 2007 May 4;282(18):13316-25. Epub 2007 Mar 7.
Sun X, Zhou Y, Otto KB, Wang M, Chen C, Zhou W, Subramanian K, Vertino PM, Dong JT.
Infrequent mutation of ATBF1 in human breast cancer.
J Cancer Res Clin Oncol. 2007 Feb;133(2):103-5. Epub 2006 Aug 24.
Zhong D, Guo L, de Aguirre I, Liu X, Lamb N, Sun SY, Gal AA, Vertino PM, Zhou W.
LKB1 mutation in large cell carcinoma of the lung.
Lung Cancer. 2006 Sep;53(3):285-94. Epub 2006 Jul 5.
Sharma D, Saxena NK, Davidson NE, Vertino PM.
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes.
Cancer Res. 2006 Jun 15;66(12):6370-8.
Sharma D, Saxena NK, Vertino PM, Anania FA.
Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways.
Endocr Relat Cancer. 2006 Jun;13(2):629-40.
Parsons MJ, Vertino PM.
Dual role of TMS1/ASC in death receptor signaling.
Oncogene. 2006 Nov 2;25(52):6948-58. Epub 2006 May 22.
Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM.
DNA motifs associated with aberrant CpG island methylation.
Genomics. 2006 May;87(5):572-9. Epub 2006 Feb 17.
Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM.
Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma.
Am J Pathol. 2004 Oct;165(4):1151-61.
Sharma D, Vertino PM.
Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene.
Cancer Biol Ther. 2004 Jun;3(6):549-50. Epub 2004 Jun 24. No abstract available.
McConnell BB, Vertino PM.
TMS1/ASC: the cancer connection.
Apoptosis. 2004 Jan;9(1):5-18. Review.
Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM.
Predicting aberrant CpG island methylation.
Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12253-8. Epub 2003 Sep 30.
Levine JJ, Stimson-Crider KM, Vertino PM.
Effects of methylation on expression of TMS1/ASC in human breast cancer cells.
Oncogene. 2003 May 29;22(22):3475-88.
Vertino PM, Sekowski JA, Coll JM, Applegren N, Han S, Hickey RJ, Malkas LH.
DNMT1 is a component of a multiprotein DNA replication complex.
Cell Cycle. 2002 Nov-Dec;1(6):416-23.
Costello JF, Vertino PM.
Methylation matters: a new spin on maspin.
Nat Genet. 2002 Jun;31(2):123-4. No abstract available.
Stimson KM, Vertino PM.
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture.
J Biol Chem. 2002 Feb 15;277(7):4951-8. Epub 2001 Dec 3.
Marfatia KA, Harreman MT, Fanara P, Vertino PM, Corbett AH.
Identification and characterization of the human MOG1 gene.
Gene. 2001 Mar 21;266(1-2):45-56.
McConnell BB, Vertino PM.
Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1.
Cancer Res. 2000 Nov 15;60(22):6243-7.
Conway KE, McConnell BB, Bowring CE, Donald CD, Warren ST, Vertino PM.
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers.
Cancer Res. 2000 Nov 15;60(22):6236-42.
Ferguson AT, Vertino PM, Spitzner JR, Baylin SB, Muller MT, Davidson NE.
Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells.
J Biol Chem. 1997 Dec 19;272(51):32260-6.
Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP.
Alterations in DNA methylation: a fundamental aspect of neoplasia.
Adv Cancer Res. 1998;72:141-96. Review.
Graff JR, Herman JG, Myohanen S, Baylin SB, Vertino PM.
Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.
J Biol Chem. 1997 Aug 29;272(35):22322-9.
Yoder JA, Yen RW, Vertino PM, Bestor TH, Baylin SB.
New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase.
J Biol Chem. 1996 Dec 6;271(49):31092-7.
Issa JP, Vertino PM, Boehm CD, Newsham IF, Baylin SB.
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis.
Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11757-62.
Vertino PM, Yen RW, Gao J, Baylin SB.
De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase.
Mol Cell Biol. 1996 Aug;16(8):4555-65.
Vertino PM, Issa JP, Pereira-Smith OM, Baylin SB.
Stabilization of DNA methyltransferase levels and CpG island hypermethylation precede SV40-induced immortalization of human fibroblasts.
Cell Growth Differ. 1994 Dec;5(12):1395-402.
Issa JP, Vertino PM, Wu J, Sazawal S, Celano P, Nelkin BD, Hamilton SR, Baylin SB.
Increased cytosine DNA-methyltransferase activity during colon cancer progression.
J Natl Cancer Inst. 1993 Aug 4;85(15):1235-40.
Celano P, Vertino PM, Casero RA Jr.
Isolation of polyadenylated RNA from cultured cells and intact tissues.
Biotechniques. 1993 Jul;15(1):26-8. No abstract available.
Vertino PM, Spillare EA, Harris CC, Baylin SB.
Altered chromosomal methylation patterns accompany oncogene-induced transformation of human bronchial epithelial cells.
Cancer Res. 1993 Apr 1;53(7):1684-9.
Yen RW, Vertino PM, Nelkin BD, Yu JJ, el-Deiry W, Cumaraswamy A, Lennon GG, Trask BJ, Celano P, Baylin SB.
Isolation and characterization of the cDNA encoding human DNA methyltransferase.
Nucleic Acids Res. 1992 May 11;20(9):2287-91.
Vertino PM, Beerman TA, Kelly EJ, Bergeron RJ, Porter CW.
Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function.
Mol Pharmacol. 1991 Apr;39(4):487-94.
Vertino PM, Bergeron RJ, Cavanaugh PF Jr, Porter CW.
Structural determinants of spermidine-DNA interactions.
Biopolymers. 1987 May;26(5):691-703. No abstract available.